Lexus's bread-and-butter ES series would benefit from this pillared coupe, shown in hybrid form, the ES350/h. The front wheel drive platform could be shared with a new Solara if Toyota decides to update that 2 door version of the Camry.
The luxury marque's performance model, the IS/F could certainly turn a few heads with two fewer doors and two less pillars. Lexus could one-up the upcoming Mercedes C coupe, which in spy shots has shown it will be pillared.
These two chops were done in 2008, but still look pretty good to me, and the cars they're based on are still in production.